NAalytics/Assemblies-of-putative-SARS-CoV2-spike-encoding-mRNA-sequences-for-vaccines-BNT-162b2-and-mRNA-1273
RNA vaccines have become a key tool in moving forward through the challenges raised both in the current pandemic and in numerous other public health and medical challenges. With the rollout of vaccines for COVID-19, these synthetic mRNAs have become broadly distributed RNA species in numerous human populations. Despite their ubiquity, sequences are not always available for such RNAs. Standard m
1,248 best points · 367 comments · 3 Hacker News posts · 3,353 GitHub stars · View on GitHub
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From the README
Assemblies-of-putative-SARS-CoV2-spike-encoding-mRNA-sequences-for-vaccines-BNT-162b2-and-mRNA-1273 version 0.21Beta 04/14/21: (updates intended to (i) clarify the clinical and research importance of sequence information and strand topology measurements, and (ii) clarify that the mRNA sequence is not a recipe to produce vaccine) Dae-Eun Jeong, Matthew McCoy, Karen Artiles, Orkan Ilbay, Andrew Fire*, Kari Nadeau, Helen Park, Brooke Betts, Scott Boyd, Ramona Hoh, and Massa Shoura* Departments of Pathology, Genetics, Pediatrics, and Medicine, Stanford University School of Medicine and Veterans Affairs Palo Alto Medical Center *Correspondence: afire@stanford.edu and/or massa86@stanford.edu…
Hacker News discussions
- Moderna mRNA sequence released to GitHub [pdf] (1,248 points, 367 comments, by aty268, 2021-03-29)
- Moderna and BioNTech mRNA sequences [pdf] (2 points, 0 comments, by MKais, 2021-03-24)
- SARS-CoV2-spike-encoding mRNA sequences for vaccines BNT-162b2 and mRNA-1273 [pdf] (2 points, 0 comments, by Anon84, 2021-03-28)