mooreneural/HelixDB

AI-native tensor format (.ptt) for structural biology ML. Convert a protein/nucleic-acid/ligand structure or sequence once; load backbone, MSA, ESM embeddings, sparse pair features, and ligand pockets with zero parsing. Feeds Boltz-2 (verified), AlphaFold 3, Chai-1, Nesso. Zarr-backed, PyTorch/JAX, streams from S3/GCS.

2 best points · 0 comments · 2 Hacker News posts · 1 GitHub stars · View on GitHub

Hacker News discussions

• ProteinTensor – a Parquet-like tensor format for protein-structure ML (2 points, 0 comments, by ramen0w0, 2026-07-02)
• The Protein Data Layer for AlphaFold-Style Models (2 points, 0 comments, by ramen0w0, 2026-07-03)